If you are looking for the best pain relief gels creams of top quality, read our detailed reviews on them here before making the purchase decision.
In Hurry? Checkout Our Top Pick Of Best Pain Relief Gels Creams.
Our Top Pick

9.7/10 our score
Best Pain Relief Gels Creams
Rank | Product Name | Score |
---|---|---|
1 ![]() |
Outback All-Natural Pain Relief – 50mL Roll-On |
9. 7 |
2 ![]() |
Penetrex Pain Relief Cream – LARGE |
9. 5 |
3 ![]() |
Sombra Warm Therapy Natural Pain Relieving Gel |
9. 1 |
4 ![]() |
Blue Emu Original Analgesic Cream |
8. 8 |
5 ![]() |
Biofreeze Pain Relief Gel |
8. 6 |
6 ![]() |
Boiron Arnicare Gel |
8. 2 |
7 ![]() |
Real Time Pain Relief Maxx |
8. 0 |
8 ![]() |
Glucosamine Pain Relief Gel |
7 .7 |
9 ![]() |
CobraZol Topical Gel Roll-On Chronic Pain Relief |
7. 4 |
10 ![]() |
Orthogel Advanced Pain Relief Gel Roll On |
7. 2 |
1. Outback All-Natural Pain Relief – 50mL Roll-On

9.7/10 our score
- 100% MONEY BACK GUARANTEE: If you don't absolutely love it, you'll get a full refund—no questions asked!
- USE ONLY AS DIRECTED: Apply Outback Pain Relief liberally to the affected area and massage it in gently until it is absorbed through the skin. If this is your first time using Outback Pain Relief, repeat this procedure 3-4 times per day over an initial period of 7-10 days, and thereafter, on an as-needed basis. The more consistently you use it, the more effective it will become. As your symptoms improve, you can reduce the frequency of applications.
- ONLY FOUR, ALL-NATURAL, GMO-FREE, AND CRUELTY-FREE INGREDIENTS: Outback Pain Relief contains only four ingredients—Tea Tree Oil, Vanilla, Blue Malle Eucalyptus, and Olive Oil. Outback Pain Relief does not include any ingredients that will induce temperature sensations, so do not expect your skin to heat up or cool down upon application.
2. Penetrex Pain Relief Cream – LARGE

9.5/10 our score
- Make sure this fits by entering your model number.
- QUICK, STRONG & LONG-LASTING: Penetrex absorbs Quickly & Easily into affected areas and goes to work instantly. Apply Penetrex to the Back, Neck, Knee, Hand, Foot, Shoulder, Elbow, Wrist, Hip, Shin, Calf, etc. Penetrex does not simply mask pain with cooling/warming sensations. Instead, Penetrex addresses the root of the problem, inflammation. Since 2009, this alternative approach to Topical Pain Management has established an unmatched track record of delivering REAL results to REAL sufferers.
- BREAKTHROUGH FORMULATION: Utilizing a Revolutionary Delivery System, Penetrex delivers Clinically Proven Ingredients including Arnica, Glucosamine, MSM (DMSO2), Choline, Boswellia Serrata, Vitamin B6 and more, deep into affected areas. Vanishing Scent / Made in the USA / Non-Greasy / Non-Staining / Paraben-Free / NEVER Tested on Animals.
- MILLIONS OF CLIENTS WORLDWIDE: Sufferers in over 100 countries have now discovered this Breakthrough Formulation. Just 2 or 3 years ago Penetrex was truly a Best Kept Secret. The WORLD now knows about this amazing formulation. This product frequently becomes Back-Ordered. Don't wait! Get Your Life Back! Order your supply of Penetrex TODAY!
- 8+ YEARS OF RESEARCH & DEVELOPMENT: Still Formulated & Filled by the Original, Renowned Chemist in Southern California. Penetrex is recommended for use on its own or in conjunction with alternative Pain Relief therapies such as braces, splints, gloves, ultrasound treatment, physical therapy & massage. Now Benefit from even Faster Shipping & Lower Prices on Penetrex!
- 100% MONEY-BACK GUARANTEE: Your Penetrex Purchase & Complete Satisfaction is Unconditionally Guaranteed by Biomax Health Products, Inc. If you are less than 100% Satisfied with Penetrex for ANY reason, we sincerely urge you to take advantage of our "No-Hassle", "No Questions Asked", "No Time Limit" Refund Policy. Simply call our U.S. based Customer Service Team at (858) 356-5980 and your Refund will be processed quickly and respectfully. "Pain-Free Results or a Pain-Free Refund."
3. Sombra Warm Therapy Natural Pain Relieving Gel

9.1/10 our score
- Absorbs quickly with a refreshing orange scent.
- Alcohol free, non-greasy, non-staining.
- Unique warming and cooling ingredients.
- Animal Free. Made in the USA
- Relieves minor aches and pains of muscles and joints associated with arthritis and simple backaches
4. Blue Emu Original Analgesic Cream

8.8/10 our score
- Soothes Joints and Muscles
- Odor Free & Non-Greasy
- Value Size
- America's #1 Emu Oil Formula
- Deep Penetrating Support
- Apply liberally as needed, for best results, apply 2-3 times daily for 2 weeks, then as needed
5. Biofreeze Pain Relief Gel

8.6/10 our score
- Clinically Recommended: Trusted by pharmacists, physical therapists, chiropractors, massage therapists, podiatrists, and athletic trainers
- Unique cooling menthol formula is backed by science and research-proven to deliver fast acting, long lasting and deep penetrating pain relief for sore muscles, backaches, sore joints, and arthritis
- Trusted by some of the world's best athletes and athletic trainers
- Colorless 4 oz. gel tube is one of the most popular formats well-suited for application on small and large muscle areas
- Biofreeze gel applies easily and penetrates quickly for fast pain relief, product is not tested on animals, made with USP grade ingredients, and free of NSAIDs, parabens, and propylene glycol
6. Boiron Arnicare Gel

8.2/10 our score
- ARNICA FOR PAIN: This homeopathic medicine helps temporarily relieve muscle pain & stiffness due to minor injuries, overexertion & falls. Also great for pain, swelling, & discoloration from bruises.
- TOPICAL PAIN RELIEF: Our non-greasy, water-based formula absorbs quickly & is unscented & paraben-free. This cooling gel is great for relief following an injury, intense workout, or general overexertion.
- PLANT-BASED ACTIVE INGREDIENT: The Arnica montana plant is a natural pain reliever. This popular homeopathic medicine temporarily relieves muscle pain & stiffness without unwanted drowsiness.
- HOMEOPATHIC MEDICINE uses highly diluted biological, botanical, or mineral substances to relieve symptoms. Our tablets, pellets, & topical treatments work with your body without the risk of contraindications, or known drug interactions.
- THE BOIRON PROMISE: We believe there’s more than one way to feel better. Since 1932, we have been committed to providing quality medicines. As a world leader in homeopathy, our passion is your health. Our promise is your satisfaction.
7. Real Time Pain Relief Maxx

8/10 our score
- Easy to Use- Real Time Pain Relief is designed for easy, everyday use. It absorbs quickly, is non-greasy, and smells great too!
- Smells Great- Unlike other pain relief lotions with a medicinal smell, Real Time Pain Relief formulas are crafted to release a wonderfully fresh smell.
- Recipe for Success- While virtually all of the name-brand topical pain relief companies utilize parabens, SLS and artificial dyes to keep their product cost down, Real Time Pain Relief is committed to not using these harmful chemicals. Additionally, Real Time Pain Relief formulas do NOT contain NSAIDs or acetaminophen.
- FDA Registered OTC- Real Time Pain Relief offers FDA Registered Over-the-Counter (OTC) drugs. All Real Time Pain Relief formulas are made in a FDA monitored facility.
- All Real Time Pain Relief formulas are made in a FDA monitored facility. Trusted Pain Relief- Thousands of Real Time Pain Relief customers have shared satisfied testimonials about finally finding pain relief that they can trust. Our family owned and operated business is proud to say that we’ve been around for over 20 years.
8. Glucosamine Pain Relief Gel

7.7/10 our score
- Targets and relieves joint and muscle aches, painful arthritis symptoms, backache, and even the pain associated with bruises!
- Easy-to-use roll-on delivers powerful, targeted relief. No mess application.
- Professional formula uses perfect balance of active Capsaicin and beneficial Emu Oil
- Capsaicin reduces Substance P, the chemical in the body that causes painful sensations
- 100% satisfaction guaranteed. If you don't like the product, just return it for a full refund, Long Trusted OTC Formula made in USA.
9. CobraZol Topical Gel Roll-On Chronic Pain Relief

7.4/10 our score
- CobraZol quickly absorbs into the skin, and relief can be felt within 10-15 minutes, and lasts.
- CobraZol helps conditions that cause lower back pain, muscle aches, and neck & joint pain.
- We can proudly say that this product is made in the USA and has NEVER been tested on animals.
- Guaranteed to Work or Your Money Back Within 90 Days!
10. Orthogel Advanced Pain Relief Gel Roll On

7.2/10 our score
- Benefits of ilex
- Optimism product
- PureFlex glucosamine